Diabetes is a chronic disease that affects millions of people around the world. Although there are many treatments available, many patients still struggle to control their blood sugar levels. Fortunately, a new class of medications called GLP-1 analogs can help change that.
What is GLP-1?
GLP-1 is a hormone produced by the small intestine that helps regulate blood sugar levels. It does this by stimulating the production of insulin and inhibiting the production of glucagon, another hormone that increases blood sugar levels. GLP-1 also helps decrease appetite and delay gastric emptying, which can help control weight.
What is the role of GLP-1 in physiology?
GLP-1 is a hormone that helps regulate blood sugar levels. It does this by stimulating the production of insulin and inhibiting the production of glucagon, another hormone that increases blood sugar levels. GLP-1 also helps decrease appetite and delay gastric emptying, which can help control weight.
What are GLP-1 analogues?
GLP-1 analogues are medications that mimic the action of GLP-1 in the body. They are used to treat type 2 diabetes and help control blood sugar levels. They can also help manage weight and reduce the risk of heart disease.
Table of GLP-1 analogues
Here is a table that lists GLP-1 analogues, their clinical indication, their route of administration and the duration of the medication’s effect:
| Analog name | Clinical indication | Route of administration | Effect duration |
| Semaglutide | Type 2 diabetes, overweight or obesity | Weekly subcutaneous injection or tablets for daily administration | 7 days (injection) or 24 hours (tablets) |
| Liraglutide | Type 2 diabetes, overweight or obesity | Daily subcutaneous injection | 24 hours |
| Albiglutide | Type 2 diabetes | Weekly subcutaneous injection | 7 days |
| Dulaglutide | Type 2 diabetes | Weekly subcutaneous injection | 7 days |
| Exenatide | Type 2 diabetes | Weekly or daily subcutaneous injection | 7 days (weekly) or 24 hours (daily) |
| Lixisenatide | Type 2 diabetes | Daily subcutaneous injection | 24 hours |
| Tirzepatide | Type 2 diabetes | Weekly subcutaneous injection | 7 days |
Conclusion
GLP-1 analogues are a new class of medications that may help manage type 2 diabetes. They mimic the action of GLP-1 in the body and help control blood sugar levels. They can also help manage weight and reduce the risk of heart disease. If you have type 2 diabetes, talk to your doctor to find out if GLP-1 analogues are a good treatment option for you.
